Cyclooxygenase (COX) catalyzes the conversion of arachidonic acid to prostaglandin and thromboxane precursors. There are 2 COX inh9ibitors (COX-1 and COX-2), with some indication of a third (COX-3).
How Pain Works:
- drug name
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- Trade name
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- Main action or classification (ex: adenosine antagonist)
- Source: synthetic, naturally ocurring, or herbal derrivative
- Where did the original mocecule come from?
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Analgesic Drug List:
Some quick example text to build on the card title and make up the bulk of the card's content.
|Brand Name(s):||Zostrix, Zostrix HP|
|Main Action:||Appears to inhibit Substance P|
|CYP450 Enzyme Metabolism||N/A|
|Common Dosage:||Topical application|
Also known as Paracetamol in some parts of the world. This is one of the safest, and most commonly used pharmaceutical drugs in the world. It has a similar action to NSAID's on pain and fever, but lacks clinical significance towards inflammation, and antiplatelet.
Although one of the safer drugs, overdose is easily accomplished, and can result in irreversible liver and kidney damage within 4-5 days. Doses within the therapeutic range are well tolerated.
|Generic Name:||Acetominophen and Paracetamol|
|Brand Name(s):||Tylenol, Silapap, Tactinal, Medi-Tabs, Mapap, Vitapap, Actamin, Anacin AF, Apra|
|Main Action:||Centrally acting inhibitor of prostaglandin synthesis from arachidonic acid.
Possible action at cannabinoid receptors in the CNS
|CYP450 Enzyme Metabolism||1A2|
|Common Dosage:||Highly variable. Visit Drugs.com.