SSRI Summary

(Selective serotonin reuptake inhibitor). 

SSRI's are the 1st line of defence for depression currently. they work by selectively inhibiting the reuptake of serotonin in the synapses, thus increasing the concentration in the synaptic cleft. 

Due to the selective nature of this class of drugs, they have less of an effect on the other monoamines present in the brain. This is likely the reason behind theiur relatively lower side effects compared to other antipsychotic drugs. 


Serotonin

 


Indications:

  • Mild to moderate depression
  • Anxiety
  • Obsessive compulsive disorder (OCD)
  • Panic disorder
  • Eating disorders
  • Post traumatic stress disorder (PTSD)

Adverse Reactions:

  • Weight loss
  • Sleep disturbances
  • Nausea
  • Diarrhea
  • Rash and hypersensitivity reactions
  • Worsened anxiety, nervousness, restlessness, agitation
  • Sexual dysfunction
  • Headache or dry mouth
     

Common Interactions:

  •  

Drugs:

Fluoxetine

INSERT

Generic Name: Fluoxetine
Brand Name: Prozac, Lovan
Main Action: Selective serotonin reuptake inhibitor
Receptor: INSERT)
Source: Synthetic
Common Dosage: xxx

Sertraline

INSERT

Generic Name: Sertraline
Brand Name: Zoloft
Main Action: Selective serotonin reuptake inhibitor
Receptor: INSERT
Source: Synthetic
Common Dosage: xxx

Citalopram

This is one of the most potent SSRI medications currently used.

Generic Name: Cipramil
Brand Name: INSERT
Main Action: Selective serotonin reuptake inhibitor
Receptor: INSERT
Source: Synthetic
Common Dosage: xxx

Paroxetine

INSERT

Generic Name: Paroxetine
Brand Name: Aropax
Main Action: Selective serotonin reuptake inhibitor
Receptor: INSERT
Source: Synthetic
Common Dosage: xxx

Fluvoxamine

This is one of the least potent SSRI medications used.

Generic Name: Fluvoxamine
Brand Name: Luvox
Main Action: Selective serotonin reuptake inhibitor
Receptor: INSERT
Source: Synthetic
Common Dosage: xxx