Caffeine is perhaps the most popular stimulant in the world. It's contained within 3 of the most popular beverages the world has ever seen; coffee, tea, and yerba maté.
Caffeine is an alkaloid that works mainly by competitively inhibiting adenosine on our neurons. Adenosine acts normally to slow the firing of our nerves, resulting in sleepiness. When caffeine inhibits these from taking action, it effectively inhibits our sleepiness.
Although not technically a nootropic, caffeine is a useful addition to nootropic formulas for its ability to give us faster reflexes, stimulate the CNS, and keep us awake when we would normally be feeling tired.
- CNS Stimulant
- Inhibits sleepiness
- Increases blood pressure
- Improves Productivity
- Adenosine antagonist
- Relaxes smooth muscle
- Stimulates cardiac muscle
- Modulates internal calcium
- Inhibits cyclic nucleotide phosphodiesterases
200 -300 mg Per day
(3-4 cups of coffee/day spread out through the day)
- Add to nootropic formulas
- Extending work efficiency
- Headaches (not all types)
200 - 300 mg/day
Equivalent to 3-4 cups of coffee split up throughout the day.
Best taken with L-Theanine and/or Theobromine.
Caffeine is a colorless, odorless, white chrystaline powder.
Very low water solubility.
One method of extraction is to boil coffee beans in water with lime or magnesium oxide to precipitate tannins and coloring matter. Charcoal may be used to remove other coloring agents, and the caffeine will rechrystalize out of the hot water easily. .
Another method is to use supercritical carbon dioxide or obtain byproduct of decaffeinated coffee or teas. .
Adenosine Receptor Antagonism
Still compiling research.
Despite previous reports online, there is no evidence for caffeine being a carcinogen.
Synergy with related alkaloid theobromine, and amino acid L-theanine.
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- Pub Chem. (n.d.). caffeine | C8H10N4O2 - PubChem. Retrieved February 17, 2017, from https://pubchem.ncbi.nlm.nih.gov/compound/caffeine#section=Methods-of-Manufacturing