Aloe (Aloe vera/barbadensis)

aloe vera herb

Aloe Summary

Aloe is a genus of succulents with sharp ridges on the leaves, and a thick, slippery gel on the inside. Aloes of all species have been used for a wide range of conditions, and is one of the longest recorded herbal medicines in human history. The use of aloe dates back to the early Egyptians, Chinese, and Roman empires. Alexander the great has been said to have conquered the island of Socotra, off the coast of Africa in order to secure Aloe growing there to heal his soldiers.

Aloe has a wide range of clinical actions both internally and externally, and remains popular amongst herbalists and product developers for anything from skin conditions, digestive complaints, liver dysfunction, and cardiovascular disease.

 

+ Indications

Internally

  • Non insulin dependant diabetes mellitus
  • Hypertriglyceridemia
  • Adjuvant treatment for HIV and AIDS
  • Improving immune response
  • Constipation

Externally

  • Herpes
  • Psoriasis
  • Seborrheic dermatitis
  • Burns
  • Mouth ulcers
  • Wounds
  • Abscesses
  • Dermatitis
  • Radiation induced dermatitis

+ Contraindications

  • Caution of hypersensitivities

Herbal Actions:

  • Antinflammatory
  • Antiviral
  • Emmolient
  • Immunomodulator
  • Demulcent
  • Anti-tumor
  • Hypocholesterolemic
  • Vulnerary
 

How Is Aloe Used?

Aloe is commonly used as a topical agent for burns, skin irritations, and eczema. The thick mucilage contained in the leaf gel has antiseptic, antinflammatory, and vulnerary actions, making it an excellent choice for general skin irritations.

Internally, aloe provides similar support for the epithelial tissue of the digestive tract. Consumed internally also offers some mild laxitive actions and hepatobiliary effects.

 

Traditional Uses

+ Western Herbal Medicine

Aloe vera (and other Aloes) have been used for a long time in various cultures, for its actions on conditions such as: anti-inflammatory, immunostimulant, antiseptic, wound and burn healing, anti-tumoral and laxative effects [5-8].

+ Traditional Chinese Medicine

Pinyin:

Lu Hui

Taste:

Bitter [13]

Energy:

Cold [13]

Channels:

Liver and large intestine [13]

Action:

Removes liver heat, improves intestinal motility [13],

Indications:

Constipation with restless insomnia due to heat accumulation [13]

Cautions:

Do not use during pregnancy or in patients with cold deficient spleen or stomach disorders [13].

+ Ayurvedic Medicine

In the Ayurvedic and Thai medicine, Aloe was used to treat peptic ulcers, burns, wounds, abscesses, mouth ulcers, and inflammation [12].

 

Daily Dose

Part Used

  • insert

Family Name

  • insert

Distribution

  • insert

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Constituents of Interest

  • CONSTITUENT
  • CONSTITUENT
  • CONSTITUENT
  • CONSTITUENT

Common Names

  • COMMONNAME
  • COMMONNAME
  • COMMONNAME
  • COMMONNAME
  • COMMONNAME

CYP450

  • Unkown

Quality

  • Unknown

Pregnancy

  • Unknown

Taste

  • Unkown

Duration of Use

  • Unknown

Part Used

Leaves

Family Name

Asphodelaceae

Distribution

South America
Africa
Mexico
Southern Regions of America

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Constituents of Interest

  • Anthraquinone glycosides
  • Acemannan

Common Names

  • Aloe
  • First Aid Plant
  • Lu Hui (China)
 

Botanical Information

Aloe is a flowering succulent plant found growing int he tropics and subtropics.

Aloe is a member of the Asphodelaceae faily of plants. This family is home to over 40 genera, and about 900 different species, 500 of which are comprised of the Aloe genus.

 

Harvesting Collection, and Preparation:

Leaf extracts containing quantified levels of the chemical acemanna are recommended (no less than 11.25 mg/ml) [12].

Aloe extracts containing low anthraquinones (through removal process) are also preferred for internal use [12].

 

Pharmacology & Medical Research

+ Atherosclerosis

Aloe vera's confirmed anti-inflammatory actions [4], as well as its hypocholesterolemic actions [8] may be the main mechanism of actions in its suggested ability to treat, and prevent atherosclerosis. Inflammation has been linked closely with the development of atherosclerosis [1, 2], and using antinflammatory medications such as Aloe vera may soon become a mainstay of treating or preventing this ultimately deadly disease process.

+ Dermatitis

The emollient actions of Aloe vera has been well studied, and has been shown to be an effective treatment in radiation induced dermatitis [1].

In burns, a topical application of Aloe gel is suggested to inhibit thromboxane B2, and prostaglandin F-2-alpha formation. This subsequently preserves dermal circulation and improves outcome of both first degree, and 2nd degree burns [12].

+ Inflammation

Aloe vera has well documented actions as an anti-inflammatory [4, 12]. The antinflammatory action is reported to rely on the prescence of anthraquinones [12].

+ Cholesterol

Aloe vera was shown to significantly reduce the atherosclerosis formation, and blood cholesterol levels of animals fed a high cholesterol diet vs those with just a high cholesterol diet [8]. This common disease process is one of the major risk factors for developing chronic heart disease, or mycocardial infarction, and stroke.

+ Antiviral

Anthraquinones extracted from Aloe barbadensis was found to inhibit the adsorption of some enveloped virus' into cells. Thus it was able to prevent the virus' from replicating. The mechanism of action was found to be through an interaction with the viral envelope. [11].

It has reported to possess activity against virus' such as HIV [12],

 

Phytochemistry

[1, 12]

Aloe vera contains roughly 75 potentially active constituents [1].

+ Constituent Summary

  • Anthraquinone glycosides
  • Polysaccharides
    • Acemannan
  • Vitamins
  • Enzymes
  • Minerals
  • Sugars
  • Lignins
  • Saponins
  • Salicylic acids
  • Amino acids
 

Clinical Applications Of Aloe:

Aloe is a useful laxitive, hepatoprotective, and for reducing triglyceride and cholesterol levels. Externally it is very uesful for treating all kinds of skin irritations, burns, and traumatic damage.

 

Cautions:

Do not use aloe internally for long periods of time.

 

Recommended Products Containing Aloe:

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Organic Aloe vera Gel

Amara Organics

99.75% Pure organic Aloe vera gel. No color, fragrance, or alcohol

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Aloe vera Powder

Bulksupplements

Dried and powdered Aloe vera

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Aloe vera Gel

Natur Sense

Cold pressed, charcoal filtered, pure aloe.


Shop Now
 

Author:

Justin Cooke BHSc

The Sunlight Experiment

(Updated November 2018)


 

Recent Blog Posts:

References:

  1. Haddad, P., Amouzgar-Hashemi, F., Samsami, S., Chinichian, S., & Oghabian, M. (2013). Aloe vera for prevention of radiation-induced dermatitis: a self-controlled clinical trial.Current Oncology, 20(4), 345. doi:10.3747/co.20.1356

  2. Vogler BK, Ernst E (1999). Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract. 49:823-8.

  3. Natural Products Insider. (2009). International Aloe Science Council presents a scientific primer on aloe. www.naturalproducts insider.com/ebooks/2009/10/iasc-presents-a-scientific-primer-on-aloe. aspx

  4. Davis RH, Leitner MG, Russo JM, Byrne ME. (1989). Wound healing. Oral and topical activity of Aloe vera. J Am Podiatr Med Assoc. 79(11):559–62.

  5. Reynolds T, Dweck AC. (1999). Aloe vera leaf gel: a review update. J Ethnopharmacol. 68(1-3):3–37.

  6. Heggers JP, Kucukcelebi A, Listengarten D, Broemel KF. (1995). Wound healing effects of Aloe gel and other topical antibacterial agents in rat skin. Phytotherapy Res. 9(6):455–7.

  7. Chithra P, Sajithlal GB, Chandrakasan G. (1998). Influence of Aloe vera on the healing of dermal wounds in diabetic rats. J Ethnopharmacol. 59(3):195– 201.

  8. Dana, N., Javanmard, S. H., Asgary, S., Asnaashari, H., & Abdian, N. (2012). The effect of Aloe vera leaf gel on fatty streak formation in hypercholesterolemic rabbits. J Res Med Sci, 17(5), 439-442.

  9. Libby P, Ridker PM. (2004). Inflammation and atherosclerosis: role of C-reactive protein in risk assessment. Am J Med. 2004;116(Suppl 6A):9S–16S.

  10. Hansson GK, Libby P. (2006). The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006;6(7):508–19.

  11. Sydiskis, R. J., Owen, D. G., Lohr, J. L., Rosler, K. H., & Blomster, R. N. (1991). Inactivation of enveloped viruses by anthraquinones extracted from plants. Antimicrobial Agents and Chemotherapy, 35(12), 2463-2466. doi:10.1128/aac.35.12.2463

  12. Bone, K. (2003). A clinical guide to blending liquid herbs: Herbal formulations for the individual patient. Edinburgh [u.a.: Churchill Livingstone. (Pg. 61-64).

  13. Wu, J. N. (2005). An illustrated Chinese materia medica. New York: Oxford University Press. (Pg 62-63).